Julia elizabeth khorana
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ProfessorHar GobindKhorana
Born9th January, 1922 (Raipur, Punjab, British India) - Died9th December, 2011 (Concord, Massachusetts, United States)
Khorana was one of the first scientists to demonstrate the role of nucleotides in protein synthesis and helped crack the genetic code. He also helped develop custom-designed pieces of artificial genes and methods that anticipated the invention of the polymerase chain reaction (PCR) process, a biochemical technology used to amplify a single or a few copies of a piece of DNA.
Har Gobind Khorana working in his laboratory at Wisconsin-Madison, late 1960s. (Photo credit: University of Wisconsin-Madison)
Family
Har Gobind Khorana was the youngest of five children, one girl and four boys. His parents were Hindu and lived in Raipur, a small village inhabited by 100 people, that is based in the Punjab, a region allocated to Pakistan after the partition of British India. It was here that Khorana was born. Khorana's father, Ganpat Rai, was a patwai (village agricultural taxation clerk) who worked for the British Indian go
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Har Gobind Khorana
Indian-American molecular biologist (1922–2011)
Har Gobind Khorana (9 January 1922 – 9 November 2011) was an Indian-American biochemist.[1] While on the faculty of the University of Wisconsin–Madison, he shared the 1968 Nobel Prize for Physiology or Medicine with Marshall W. Nirenberg and Robert W. Holley for research that showed the order of nucleotides in nucleic acids, which carry the genetic code of the cell and control the cell's synthesis of proteins. Khorana and Nirenberg were also awarded the Louisa Gross Horwitz Prize from Columbia University in the same year.[2][3]
Born in British India, Khorana served on the faculties of three universities in North America. He became a naturalized citizen of the United States in 1966,[4] and received the National Medal of Science in 1987.[5]
Biography
Har Gobind Khorana was born to Ganpatrai Khorana and Krishna Devi, in Raipur, a village in Multan, Punjab, British India, in a Punjabi HinduKhatri family.[6] The exact date of his birth is not c
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Biographical Memoir published on Har Gobind Khorana, Nobel Laureate and Former Alfred P. Sloan Professor of Biology and Chemistry
A biographical memoir on the inimitable Har Gobind Khorana has been written by Phillip A. Sharp, Institute Professor and Professor of Biology Emeritus and Intramural Faculty, Koch Institute, and Uttam L. RajBhandary, the Lester Wolfe Emeritus Professor of Molecular Biology and published online via the National Academy of Sciences.
Khorana, a Nobel Laureate who shared the 1968 Nobel Prize in Physiology or Medicine with Robert Holley and Marshall Nirenberg “for their interpretation of the genetic code and its function in protein synthesis”, joined the MIT faculty in 1970. He remained the Alfred P. Sloan Professor of Biology and Chemistry until transitioning to Emeritus status in 2007.
Sharp and RajBhandary’s biography encompasses Khorana’s incredible life, which began in a small village in India, and culminated in his death in 2011, with nearly nine decades of illustrious discovery and invaluable contributions in between.
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